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Issued 2022
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KPTI$0.0901-19.55%
Karyopharm Therapeutics Inc.
Sector: Pharmaceutical PreparationsIndustry: BiotechnologyCountry: USExchange: Nasdaq
Mkt Cap:$2.04M
Float & O/S:
Inst Own:
DilutionScan read 54 of Karyopharm Therapeutics Inc.'s SEC filings and found 9 warrant series, 5 convertibles, 1 ATM program, 6 shelf registrations and 7 completed offerings on file for KPTI. The latest dilution event on file is an offering on Sep 17, 2026. Analysis updated Nov 3, 2026.
Signal8 Summary
KPTI
Going-concern warning from auditors
Snapshot
Karyopharm is a commercial-stage biotech with a healthy product gross margin (96%) but a deeply strained balance sheet. The company generates roughly $146M in revenue, yet spends heavily on R&D and sales (158% of revenue combined), leading to a $196M net loss and a $75M annual cash burn.
What's Happening Right Now
- : The Phase 3 endometrial cancer trial missed its primary endpoint, and the company plans to reduce investment in that area to prioritize myelofibrosis and multiple myeloma programs.
- : Karyopharm plans to submit a supplemental New Drug Application in August 2026 for accelerated approval of selinexor plus ruxolitinib in myelofibrosis.
- : The company disclosed a going-concern warning in its Q1 2026 10-Q, stating there is substantial doubt it can continue operating within one year without raising additional capital.
Raise routes on file: active ATM + effective shelf · latest dilution event 47 days ago
Overall Risk
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AI dilution summary
The dominant contractual driver and its mechanism, then each further driver ranked.
Latest dilution event
Sep 17, 2026 · Offering
Every warrant, convertible, ATM and shelf, cited to the filing
A free account reads 3 tickers a day in full
$59/mo with 7 days free, or $49/mo billed yearly ($588/yr)
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Outstanding
Warrant
Issued 2024
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2025 Placement Warrants
Issued 2025
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2025 Warrants – 2025 Notes exchange tranche
Issued 2025
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Warrant
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Senior Secured Convertible Notes due 2029 (New 2029 Notes)
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Senior Secured Convertible Notes due 2028 (2028 Notes)
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Convertible
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Convertible Senior Notes due 2025 (2025 Notes)
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Series A Convertible Perpetual Preferred Stock
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ATM program
Issued 2023
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S-3 shelf registration
Issued 2026
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S-3 shelf registration
Issued 2023
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S-3 shelf registration
Issued 2026
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Issued 2025
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Issued 2024
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PIPE
Issued 2026
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Issued 2025
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Know who's about to sell into your KPTI trade
Exercise prices, conversion terms, shelf headroom and the filing sentence behind every number.
$59/mo with 7 days free, or $49/mo billed yearly ($588/yr)
